Getting into the groove
نویسندگان
چکیده
منابع مشابه
Protein targeting: Getting into the groove
The 54 kDa subunit of the signal recognition particle has to identify a diverse family of substrates and deliver them in a controlled manner to the translocation machinery of the endoplasmic reticulum. Important new insights into the function of this sorting protein have emerged from recent biochemical and structural studies.
متن کاملDevelopment: Getting into the Groove, or Evolving off the Rails?
Canalization, the robust buffering against fluctuations, is often regarded as an essential feature of development. A new study identifies a genetic circuit dedicated to canalization in Drosophila melanogaster and shows striking variability in its use in different fly species.
متن کاملGetting the Groove into Silicone – Let Light Do the Job
Patterned deep UV-irradiation of cured polydimethylsiloxane (PDMS) followed by wet-chemical etching is a convenient method to create microstructures in this material with structural depths up to 10 μm. The intrinsic elasticity of many polydimethylsiloxanes allows the introduction of a new parameter influencing the patterning process: elongation. Symmetric stretching during the irradiation, subs...
متن کاملProtein–RNA interactions: Getting into the major groove
RNA–protein interactions are involved in many cellular processes, including information storage and transfer, catalysis and transcriptional activation. Our structural knowledge of these interactions at atomic resolution is based on X-ray crystallographic and nuclear magnetic resonance (NMR) studies (for a review see [1]). The crystal structures of a number of RNA–protein complexes have been rep...
متن کاملGetting the embryo into shape
Membrane backtracking T he inner membrane of a chloroplast bristles with enzymes and other proteins that are synthesized in the cytoplasm, but how they get into position is uncertain. On page 249, Li and Schnell report that at least some proteins pass through the inner membrane and reenter it from the back side, rather than stopping on the way through. Chloroplasts are swaddled by inner and out...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Nature
سال: 1989
ISSN: 0028-0836,1476-4687
DOI: 10.1038/342617a0